2023-05-052023-05-052022COSTA, Leilane Custodio; LOBO, Mayara Cristina Pereira. Vitiligo: aspectos clínico-epidemiológicos e associação com os níveis séricos de 25-hidroxivitamina D em um serviço de dermatologia na Amazônia. Orientadora: Silvia Ferreira Rodrigues Müller. 2022. 70 f. Trabalho de Curso (Bacharelado em Medicina) - Faculdade de Medicina, Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, 2022. Disponível em: https://bdm.ufpa.br:8443/jspui/handle/prefix/5610. Acesso em:.https://bdm.ufpa.br/handle/prefix/5610Vitiligo is a chronic disease characterized by dyschromic patches on the skin and mucous membranes resulting from the destruction of functional melanocytes in the epidermis. Its etiopathogenesis is unknown, but it is currently considered an autoimmune disease. Vitamin D has been linked to Vitiligo due to its autocrine immunoregulatory function in immune cells. The aim of the present study was to analyze the serum levels of 25-­hydroxyvitamin D in patients with Vitiligo and healthy individuals without Vitiligo, considering the clinical and epidemiological characteristics of the patients. An analytical cross-­sectional study was carried out in the period from 2017 to 2021 in a public hospital of reference in Dermatology in the city of Belém, where data were collected from 79 patients from the Vitiligo Group and 3,215 individuals from the No Vitiligo Group who had serum levels of 25-­hydroxyvitamin D The clinical-­epidemiological variables in the Vitiligo Group were gender, age, phototype, clinical form, disease duration, lesion extension, lesion activity, family member, triggering emotional factor and education. The study sample consisted of the prevalence of females (70.89%) with a mean age of 34.3 years for both sexes in the Vitiligo Group. The majority (52.08%) of the Vitiligo Group had low serum levels of 25-­hydroxyvitamin D and 86.96% of the No Vitiligo Group had levels within the normal range. However, no statistical differences were found in the 25­-hydroxyvitamin D levels of the Vitiligo Group when compared to the No Vitiligo Group. Finally, as in previous studies in the vitiligo population, lower levels of 25­hydroxyvitamin D concentration were not found in relation to the general population.Acesso AbertoVitiligoVitamina DDoença autoimuneVitamin DAutoimmune diseaseCNPQ::CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA::DERMATOLOGIATrabalho de Curso - Graduação - Monografia