2023-09-042023-09-042022ASSUNÇÃO, Darah Klyssia Mendonça; ROCHA, Leonardo Sousa. Avaliação dos testes bioquímicos hepáticos em pacientes internados com COVID-19 em um hospital de referência da região norte do país. Orientadora: Simone Regina Souza da Silva Conde. 2022. 68 f. Trabalho de Curso (Bacharelado em Medicina) - Faculdade de Medicina, Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, 2022. Disponível em: https://bdm.ufpa.br:8443/jspui/handle/prefix/6088. Acesso em:.https://bdm.ufpa.br/handle/prefix/6088Introduction: the novel coronavirus (SARS-CoV-2), causative agent of COVID-19, was acknowledged by the World Health Organization as the cause of the pandemic that started at the beginning of 2020. This infection presents itself in different ways, varying between asymptomatic and serious, fatal natures, with systemic, inflammatory and thrombotic occurrences. Researches show that the analysis of laboratory parameters allows to establish a prognosis, therefore the most appropriate management of this new human infection. Goals: to describe admitted patients epidemiological profile and correlate the hepatic biochemical alterations with their respective clinical developments. Material and methods: A cross-sectional, descriptive and observational study, performed in a benchmark hospital at the north of Brazil with mild and serious cases of COVID-19, diagnosed with nasal swab’s RT PCR. The data was obtained by analyzing medical records, selecting patients of both sexes, over 18 years of age, and whose records allowed the standard protocol to be completely filled out. This research obtained the consent of the local Human Research Ethics Committee. Results: In the period under study, from 176 hospitalizations, 96 medical records were selected, being 51 (53%) admitted to the Intensive Care Unit and 45 (47%) admitted to ward beds. There was a predominance of the male gender and mean age (58.5 years) in both groups, with greater precedence being Belém and the metropolitan region (54% against 46%). Regarding laboratory data, higher levels of AST, ALT, CRP, urea and creatinine were found in ICU patients, with mechanical ventilation and death rates of 62.4% and 58%, respectively. Conclusion: the results of this study show that among the hepatic biochemical tests, there was a correlation of the higher levels of transaminases with greater severity of the disease and with a more reserved prognosis, being necessary to expand the casuistic for more definitive conclusions.Acesso AbertoCOVID-19Marcadores bioquímicos hepáticosEvolução clínicaPrognósticoHepatic biochemical markersClinical evolutionPrognosisCNPQ::CIENCIAS DA SAUDE:: MEDICINATrabalho de Curso - Graduação - Monografia