2022-11-182022-11-182006SOUSA, Selma Parente; LIMA, Suellen Barreto. Estudo prospectivo das alterações hepáticas em gestantes internadas em um hospital de referência de Belém-Pará. Orientadora: Simone Regina Souza da Silva Conde. 2006. 76 f. Trabalho de Curso (Bacharelado em Medicina) - Faculdade de Medicina, Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, 2006. Disponível em:https://bdm.ufpa.br:8443/jspui/handle/prefix/4702. Acesso em:.https://bdm.ufpa.br/handle/prefix/4702The liver disease in pregnancy constitute a problem for the obstetrician and also for the general prationer, particulary the pregnant women with jaundice, influencing for a worst maternal-infant prognostic. The objective of this study was to determine the frequency of abnormal liver function tests in pregnant women, being classified them in related or not with the pregnancy, as well as evaluate the maternal-infant prognostic. In the period of March of 2005 to February of 2006, the pregnant women that were interned in the infirmary of high risk of the Hospital Fundação Santa Casa de Misericórdia do Pará (HFSCMPA) had made the exams of alanine-aminotransferase (ALT), aspartate-aminotransferase (AST), gamma glutamyl-transpeptidase (GGT) and bilirubins. When at least one of this tests had any alteration, it was made a extended inquiry, with biochemical examinations, sorological tests, cultures and other tests of image necessarys to the diagnostic, and had also their evolution followed. After this phase, the patients had been divided in goup I (illnesses related with the gestation) and group II (illnesses unrelated with the gestation). From the total of 480 evaluated patients, 308 (64,2%) had been included on the study, from that, 215 (69,8%), did not presented any alteration of the liver function tests, whereas 93 (30,2%) had one or more abnormalities of these tests. Whereby, 42 (45,2%) had been classified in group I and 51 (54,8%) in group II. The age of the pregnants was between 13 to 41 years, with average of 24,6 years in group I and 23,9 in group II. About the origin of the patients, it had a predominance of Belém and region in both groups, with 58,3% and 60,9% respectively. In the group I, the hipertensive disorder of pregnancy was the most frequent pathology and it was found in 71,4% of the cases; whereas in group II, the most frequent pathology were those related to the infectious diseases, with 58,8%. The majority of the patients were in the third trimester of pregnancy, with 85,7% (36/42) and 77,8% (40/51) in groups I and II respectively. The average of the bilirubins levels had been bigger in group II with a p<0,05, however, the other tests had been similar in both groups. The evolution to childbirth occurred in 78,6% in group I and 27,5% in group II, having a clear statistic significance (p=0,0001). The fetal complications had been observed in 57,6% of the cases in group I and 37,5% in group II, however without significant diference between both groups. The liver disease occurred in 30,2% of the pregnants women and the most prevalent cause of this pathology was the unrelated diseases with the pregnancy (54,8%), and it was observed that it exists a high risk of fetal complication in the group of patients with related diseases with the pregnancy.Acesso AbertoTestes hepáticosGestaçãoPrognósticoLiver function testsGestationPrognosticCNPQ::CIENCIAS DA SAUDE::MEDICINATrabalho de Curso - Graduação - Monografia