2025-03-102025-03-102024-03-15SILVA, Fernanda Protázio. Avaliação da evolução da densidade mineral óssea em pessoas vivendo com hiv/aids: um estudo longitudinal. Orientadora: Rosana Maria Feio Libonati. 2024. 53 f. Trabalho de Curso (Bacharelado em Medicina) - Faculdade de Medicina, Instituto de Ciências Medicas, Universidade Federal do Pará, Belém, 2024. Disponível em:https://bdm.ufpa.br/jspui/handle/prefix/7815. Acesso em:.https://bdm.ufpa.br/jspui/handle/prefix/7815People living with HIV/AIDS (PLWH) more frequently present changes in bone mineral density. The aim was to analyze the evolution of bone mineral density in PLWH. Thus, medical record data and bone densitometry (DXA) results were collected from an initial and final moment; patients over 18 years old, using antiretroviral therapy (ART) treated between 2017 and 2024, at the outpatient clinic of the Núcleo de Medicina Tropical (NMT), in a city in northern Brazil, were included. Data from 53 PLWHA were analyzed. Mean age was 59.4 years, male prevalence (52.8%), median CD4 T lymphocyte count was 754 cells/cm², predominance of undetectable viral load (92.5 %), high prevalence of tenofovir use (66%) and HIV infection and ART average time were 18.83 and 18.37 years, respectively. Main comorbidities were dyslipidemia (79,2%) and lipodystrophy (58,5%). In the sample, there was a prevalence of low bone mineral density (osteopenia and osteoporosis), with 67,9% in the initial and 62.2% in the final evaluation, and hypovitaminosis D (60.4%). Risk factors associated with low bone mineral density in PLWH were older age (p= 0.002) and female gender (p= 0.019). Comparing the initial and final DXA of each patient, 75.5% showed improvement or stability in bone mineral density. Lumbar spine T-score values improved (p= 0.007), with a percentage increase of 15.6%. Clinical monitoring of PLWH is essential to track and early treat the occurrence of comorbidities, including osteometabolic abnormalities.Acesso AbertoHIVOsteoporoseDensidade ósseaTerapia antirretroviral de alta atividadeOsteoporosisBone densityHighly active antiretroviral therapyCNPQ::CIENCIAS DA SAUDE::MEDICINATrabalho de Curso - Graduação - Monografia