2026-02-232026-02-232025-03-21BANDEIRA, Geisa Carvalho. Aspectos clínicos, epidemiológicos e ambientais da Leishmaniose tegumentar americana na Amazônia brasileira. Orientador: Kaio Vinícius Paiva Albarado; Coorientadora: Aldine Cecília Lima Coelho. 2025. 50 f. Trabalho de Conclusão de Curso (Bacharelado em Medicina) - Faculdade de Medicina, Campus Universitário de Altamira, Universidade Federal do Pará, Altamira, 2025. Disponível em: https://bdm.ufpa.br/handle/prefix/9238. Acesso em:.https://bdm.ufpa.br/handle/prefix/9238Leishmaniasis is a zoonosis that belongs to the group of neglected tropical diseases (NTDs) since it occurs in the poorest countries and affects extremely vulnerable populations in the Americas, Africa and Asia. This study investigated the clinical, epidemiological and environmental aspects of American Tegumentary Leishmaniasis (ATL) in the Xingu Integration Region, in Pará, Brazil, between 2009 and 2021, with the aim of analyzing the distribution of cases, calculating incidence rates and relating environmental and climate changes with the occurrence of the disease. The research, of an ecological nature, used secondary data from the Department of Information Technology of the Unified Health System (DATASUS), the Information System for Notifiable Diseases (SINAN), the National Institute of Meteorology (Inmet), in addition to information on deforestation, hotspots and land use obtained from public sources. Sociodemographic, clinical, environmental, and climatic variables were analyzed using descriptive statistical methods and Pearson's correlation to identify possible associations. The results showed 8,181 cases of ACL in the period, with a higher incidence in men (78.22%), brown skin (69.18%), and in the age group of 20 to 39 years (47.99%). The predominant clinical form was cutaneous (97.73%), with a high cure rate (86.52%). The municipalities of Medicilândia, Uruará, and Altamira had the highest numbers of cases. A significant increase in deforestation was observed, especially in Vitória do Xingu (805.36%), Pacajá (615.83%), and Brasil Novo (538.52%), in addition to a peak in hotspots in 2017 (9,348 cases). The climate analysis revealed an average annual temperature of 25.9°C and precipitation of 170.9 mm, with a 5% decrease in relative humidity between 2010 and 2015. The negative correlation between humidity and deforestation (r = -0.841) suggested that microclimatic changes may enhance the transmission of ATL. It was concluded that the expansion of agricultural activities, urbanization and large infrastructure projects, such as the Belo Monte Hydroelectric Power Plant, increased ecological and social vulnerability, facilitating the proliferation of sand flies and the occurrence of ATL. The study highlighted the need for integrated public policies, aligned with the Sustainable Development Goals (SDGs), to mitigate environmental and health impacts in the Amazon region.Acesso AbertoLeishmaniose Tegumentar AmericanaEcologia de vetoresEpidemiologia descritivaSaúde pública-AmazôniaCutaneous LeishmaniasisDisease vectorsDescriptive epidemiologyEnvironmental healthAmazonian ecosystemCNPQ::CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA::DOENCAS INFECCIOSAS E PARASITARIASTrabalho de Curso - Graduação - MonografiaAttribution-NonCommercial-NoDerivs 3.0 Brazil