2022-11-082022-11-082009GUEDES, Paulo Roberto Vieira; MEDEIROS, Thairon Mesquita. “Pesquisa de fungos e bactérias por meio de cultura microbiológica em secreção nasal de pacientes com polipose nasossinusal”. Orientador: Murillo Freire Lobato. 2009. 44 f. Trabalho de Curso (Bacharelado em Medicina) - Faculdade de Medicina, Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, 2009. Disponível em:https://bdm.ufpa.br:8443/jspui/handle/prefix/4649. Acesso em:.https://bdm.ufpa.br/handle/prefix/4649Nasal polyposis is a chronic inflammatory disease involving the nose and paranasal sinuses, with physiopathogenesis not yet fully elucidated. Affect the quality of life and may even, on rare occasions, moving with lethal complications. Objective: To evaluate the incidence of positive findings for fungi and bacteria by specific cultures of nasal secretion. Casuistic and Methods: Microbiological-surgical-prospective-cross study, with analysis of the culture of secretion collected from middle meatus and paranasal sinuses of 63 patients who underwent endoscopic surgery of polypectomy at the University Hospital Bettina Ferro de Souza in the period September 2007 to February 2008. Cultures made at the Evandro Chagas Institute. Results: In this sample, was observed that 35 patients were female (55.6%) and 25 males (44.4%). The age group most affected was the 33-37 years with 15 cases (23.8%). The culture was positive in 52 cases (82.54%), and in this percentage was found 64 different types of microorganisms, where in 62 patients (96.88%) were aerobic bacteria, one case of anaerobic (1, 56%) and another of fungus (1.56%). Among the aerobic bacteria, gram positive prevailed in 51 cases (80.95%), while Staphylococcus epidermidis was isolated in 20 samples (31.25%), followed by Staphylococcus aureus in 18 (28.13%). The Bacterioides fragilis was the only anaerobic isolated in only one case (1.56%), as well as Aspergillus fumigatus was the only species of fungus found in one patient. In 17 patients (32.69%) was growth of mixed microbial flora, and in 16 cases (94.12%) was found two concurrent bacterial and only one case (5.88%) was isolated fungi with bacteria. Conclusion: infection by microorganisms in patients with nasal polyposis is present in a large percentage of the sample prevailing aerobic gram-positive bacteria, with S. epidermidis the most frequent. Only one patient was found positive mycological culture, isolating the A. fumigatus. The possible bacterial competition may have led to false negative results of fungal cultures, requiring histopathological examination to confirm the presence of fungi in the material.Acesso AbertoPolipose nasossinusalCulturaBactériasFungosNasossinusal polyposisCultureBacteriaFungiCNPQ::CIENCIAS DA SAUDE::MEDICINATrabalho de Curso - Graduação - Monografia