2026-02-252026-02-252025-03-21ROCHA, Ana Luísa Barbosa da. Mortalidade por câncer no Pará: o caso da Região de Saúde Xingu. Orientadora: Ilka Lorena de Oliveira Farias; Coorientadora: Tracy Martina Marques Martins. 2025. 48 f. Trabalho de Conclusão de Curso (Bacharelado em Medicina) - Faculdade de Medicina, Campus Universitário de Altamira, Universidade Federal do Pará, Altamira, 2025. Disponível em: https://bdm.ufpa.br/handle/prefix/9242. Acesso em:.https://bdm.ufpa.br/handle/prefix/9242Introduction: Neoplasia is a medical term that refers to the abnormal growth of cells, forming a tumor or neoplasm. They are classified according to histological and pathophysiological aspects into benign, malignant, or mixed. Malignant neoplasms are collectively referred to as cancers, which have the potential to lead to death, with global rates of one in six deaths related to this disease. Thus, cancer is understood as a life-threatening condition, making it a significant public health issue that requires constant study and surveillance. Methodology: This is an epidemiological, descriptive ecological study with a quantitative approach, using secondary data on mortality due to malignant neoplasms in the Xingu Health Region of Pará from 2007 to 2023, collected from the Mortality Information System (SIM). Results: It was observed that during the study period, the number of deaths in the Xingu Health Region increased, rising from 70 cases in 2007 to 220 in 2023. Malignant neoplasms of the Bronchi and Lungs (11%), Prostate (10.3%), Stomach (9%), Cervix (6.2%), and Liver and Intrahepatic Bile Ducts (5.7%) were the five cancer categories that caused the most deaths and mortality in the region during the study period. The deaths mostly occurred among the male population (57.2%), in the elderly age group (56%), of mixed race (66%), with a low level of education (28,1%), and with married civil status (41%). Compared to the State of Pará and Brazil, the Xingu Health Region showed the highest percentage growth in the average mortality rate over the 17-year period. Discussion: The increase in the number of deaths in the Xingu Health Region between 2007 and 2023 may be associated with the construction of the Belo Monte Hydroelectric Plant, which profoundly changed the social dynamics of the locality, also impacting the health of the local population. The COVID-19 pandemic caused a temporary reduction in deaths and mortality in the region between 2020 and 2021, followed by a subsequent increase in deaths. The five malignant neoplasms that cause the most deaths in the Xingu Health Region show specific behaviors related to mortality, arising from the context in which the region is situated. The findings for the variables gender, age, race/ethnicity, education, and marital status are similar to those found in the literature. Conclusion: Cancer is a major public health issue, causing significant morbidity and mortality worldwide, with the Xingu Region showing substantial growth over the 17 years studied. Thus, studies aimed at understanding local and regional cancer mortality scenarios, as well as the existing care lines in these localities, are essential to establish prevention, treatment, and control policies, thereby reducing the impact of the disease on the populations' lives.Acesso AbertoNeoplasias malignasMortalidadeEpidemiologiaMalignant neoplasmsMortalityEpidemiologyCNPQ::CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA::CANCEROLOGIATrabalho de Curso - Graduação - MonografiaAttribution-NonCommercial-NoDerivs 3.0 Brazil