2023-06-272023-06-272019-05AGUIAR, Gilvane Pereira; PEREIRA NETO, Joaquim. Prevalência e fatores associados aos casos de lesões intraepitelial cervical de alto grau na unidade de referência especializada de Belém – PA. Orientadora: Maria Francisca Alves. 2019. 63 f. Trabalho de Curso (Bacharelado em Medicina) – Faculdade de Medicina, Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, 2019. Disponível em: https://bdm.ufpa.br:8443/jspui/handle/prefix/5793. Acesso em: .https://bdm.ufpa.br/handle/prefix/5793Cervical cancer is considered one of the most serious public health problems in the world with around 500,000 new cases a year, accounting for the death of about 230,000 women. Risk factors for cervical lesions of high grade although much studied, still need to be known in each population and in each period. Objective: The objective of this study was to evaluate the prevalence and factors associated with High Grade Cervical Intraepithelial Lesions (HSIL) in women attended at the Maternal and Child Reference Unit of Belém (UREMIA). Methodology: The study was observational of the transversal type, with quantitative approach using the program Bioestat 5.3. The data were collected in the period between January and December 2017 through the patient records sent to a Maternal-Child and Adolescent Specialized Reference Unit (UREMIA). Results: A total of 335 women with colpocitological diagnosis of intraepithelial lesion (SIL or LIE) were evaluated. Confirmation of the degree was through the histopathological examination performed in the ERU: High Grade Intraepithelial Lesion (HSIL) and Low Grade Intraepithelial Lesion (LSIL). The sample was divided into two groups: one group diagnosed with LIEAG (GAG) with 282 cases (84.17%), and one group with LIEBG (GBG) with 53 cases (15, 82%). In the epidemiological and clinical profile of GAG, young adults (40.8%) came from the capital (58.5%), with incomplete primary education (59.2%), living with their partner (73%) and up to 1 minimum wage (62.4%), with no pre-existing pathologies, no routine medications and no history of neoplasms in the family. They did not use tobacco and illicit drugs, but in relation to the use of alcoholic beverages was inverse (55.3%) being statistically significant. The menarche was over 12 years of age, the sixteenth age of 20 and the number of partners up to 3. Half of the GAG (50.7%) used contraceptives and of these only half used condoms (54.7%). With regard to active sexual life, 243 cases (86.2%) were found, a prevalence ratio of significant value (p = 0.0252). In the history of cervical disease, the highest frequency in GAG was in women diagnosed with HPV (n = 181, 64.2%), previous cervical lesion (65.6%) and = 180, 63.8%). The factors associated with HSIL were alcohol use and active sex life, with the value for the Ratio of significant prevalence (p = 0.0277) and (p = 0.0252) respectively. Conclusion: The prevalence of HSIL in this study was 84 , 18%. The associated variables were alcohol use and active sexual life. The epidemiological and clinical profile is similar to those of other studies, reinforcing attention to these cases, which has a greater tendency for the development of HSIL and cervical cancer. It is necessary to implement governmental programs with this attention, as well as the training of health professionals and elaboration of periodic educational actions in every region to the target public.Acesso AbertoLesão intraepitelial cervical de alto grauPrevalênciaBelémPrevalenceHigh-grade cervical intraepithelial lesionsCNPQ::CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA::ORTOPEDIATrabalho de Curso - Graduação - Monografia