2023-01-132023-01-132008NUNES JÚNIOR, Laércio Pereira. Avaliação etiológica da doença hepática crônica em um ambulatório de referência. Orientadora: Simone Regina Souza da Silva Conde. 2008. 70 f. Trabalho de Curso (Bacharelado em Medicina) - Faculdade de Medicina, Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, 2008. Disponível em: https://bdm.ufpa.br:8443/jspui/handle/prefix/4970. Acesso em:.https://bdm.ufpa.br/handle/prefix/4970The chronic liver disease (CLD) represents the eighth cause of death in the world, among non-infectious diseases. This study had the objective of identify major causes of CLD in a reference outpatient department at Belém city, as well as to correlate with demographic aspects and the clinic syndrome presentation. On the period of january to december of 2007, were selected patients with CLD diagnosis, attended in a reference outpatient department of Fundação Santa Casa de Misericórdia do Pará. The patients were submitted to clinical epidemiological investigation and to complementary examination, such as: bioquimical, hematological, serological, ultrasound, endoscopic and/or liver histopathology. The serologic and molecular biology examination were performed at Instituto Evandro Chagas and the specimens of liver biopsy were analyzed at the Departamento de Patologia da Universidade Federal do Pará. Were considerate carries of viral CLD the cases with positivity to HBsAg and HCV-RNA by qualitative PCR, apart from been considerate alcoholic person those who ingest more than 50g ethanol/day for a period superior to 5 years. From the patients analyzed, were selected 173, which were composed 51,4% of men, with 50,6 + 14,8 years-old as average age, prevailing the ages above 40 years-old. The ethnic group of most occurrence was brown people in 89,6% and 63% were married. Between the identified causes, the chronic hepatitis B (27,1%) and C (50,2%) and alcohol abuse (19) had distinction. The HCV was present in 59,6% of the chronic hepatitis and 50% of the liver cirrhosis cases (p<0,05). On this group, the female gender prevailed, with average age between 50,3 and 59,7 years-old, most married (p<0,05) and originated from metropolitan region of Belém. The positive cases to HBV occurred in 38,6% and 16,6% of the chronic hepatitis without or with cirrhosis, in this order. The chronic hepatitis B prevailed among the male gender with average age between 36,6 a 42,7 years-old, most married and 40,4% originated from the country. The abuse of alcohol isolated was present in 2,1% of the cases of chronic hepatitis and 6,7% of cirrhosis. The average age was superior among the cirrhosis (66,5 years-old), did not have difference between the married and single population and the origin was the urban centers. Therefore, to conclude, on the population of the study prevails the chronic viral hepatitis B and C and the alcoholism as major causes of CLD, the VHC had the most occurrence between the cases of chronic hepatitis with or without cirrhosis and among women; on chronic hepatitis B was noticeable a lesser average age and more cases originated from the country.Acesso AbertoDoença hepática crônicaEtiologiaEpidemiologiaChronic liver diseaseEtiologyEpidemiologyCNPQ::CIENCIAS DA SAUDE::MEDICINATrabalho de Curso - Graduação - Monografia