Fracture Risk with Modified FRAX in Men Living with HIV
| dc.contributor.advisor1 | LIBONATI, Rosana Maria Feio | |
| dc.contributor.advisor1Lattes | http://lattes.cnpq.br/3818175484709618 | pt_BR |
| dc.contributor.advisor1ORCID | https://orcid.org/0000-0002-1425-7806 | pt_BR |
| dc.creator | BRITO, Kamylla Batista | |
| dc.creator.Lattes | http://lattes.cnpq.br/5610959013891401 | pt_BR |
| dc.creator.ORCID | https://orcid.org/0009-0009-6589-7262 | pt_BR |
| dc.date.accessioned | 2025-03-12T17:41:48Z | |
| dc.date.available | 2025-03-12T17:41:48Z | |
| dc.date.issued | 2024-11-13 | |
| dc.description.abstract | Background: Aging of the HIV-infected population and prolonged use of ARTs, produced metabolic alterations, including increased fracture risk. FRAX is a validated, computer-based clinical fracture risk calculator which estimates 10-year risk of major fracture, and hip fracture. However may underestimate risk in HIV-infected individuals. Several experts recommend considering HIV a cause of secondary osteoporosis. Methodology: Were included 52 men living with HIV, classified as high, moderate and low risk using ABRASSO graphic tool. Results: High risk prevalence found for major fracture and hip fracture were both 2 (4.2 %) using FRAX; while 10 (20.8 %) and 14 (29.2 %) using modified FRAX, respectively. Considering bone densitometry, 5 (12.8 %) were high risk for hip fracture and was noticed an increase in high risk major fracture from 4.2 % with FRAX to 5.1 % with FRAX considering bone densitometry. As for the low risk, 19 (39.6 %) for major fracture and 23 (47.9 %) for hip fracture with FRAX. While low risk modified FRAX were 0 (0 %) for major fracture and 8 (16.7 %) for hip fracture. It was also evidenced an association of high risk for major fracture and hip fracture with modified FRAX using Fisher's exact test [p=0.0273 (bilateral)]. Conclusion: It was concluded is recommended using modified FRAX for people living with HIV for better control and therapeutic decision-making about osteometabolic alterations provocated for the virus and ARTs. | pt_BR |
| dc.identifier.citation | BRITO, Kamylla Batista. Fracture Risk with Modified FRAX in Men Living with HIV. Orientadora: Rosana Maria Feio Libonati. 2024. 05 f. Trabalho de Curso (Bacharelado em Medicina) - Faculdade de Medicina, Instituto de Ciências Médicas, Universidade Federal do Pará, Belém, 2024. Disponível em: https://bdm.ufpa.br/jspui/handle/prefix/7839. Acesso em:. | pt_BR |
| dc.identifier.uri | https://bdm.ufpa.br/jspui/handle/prefix/7839 | |
| dc.rights | Acesso Aberto | pt_BR |
| dc.source.uri | Disponível na Internet via correio eletrônico: bibsaude@ufpa.br | pt_BR |
| dc.subject | Fracture risk | pt_BR |
| dc.subject | HIV | pt_BR |
| dc.subject | Modified FRAX | pt_BR |
| dc.subject.cnpq | CNPQ::CIENCIAS MEDICAS::MEDICINA | pt_BR |
| dc.title | Fracture Risk with Modified FRAX in Men Living with HIV | pt_BR |
| dc.type | Trabalho de Curso - Graduação - Artigo | pt_BR |