Disease activity Score 28 in patients with Chikungunya virus infection

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dc.contributor.advisor-co1SOUSA, Rita Catarina Medeiros
dc.contributor.advisor-co1Latteshttp://lattes.cnpq.br/3560941703812539
dc.contributor.advisor-co1ORCIDhttps://orcid.org/0000-0002-8330-6667
dc.contributor.advisor1CALDAS, Cezar Augusto Muniz
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/0204781177047305pt_BR
dc.contributor.advisor1ORCIDhttps://orcid.org/0000-0002-1141-1281pt_BR
dc.creatorSÁ, Angela Beatriz de
dc.creatorGOMES, Anna Carolina Padilha Castro
dc.creator.Latteshttp://lattes.cnpq.br/6929774406019321pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/0632575969392563
dc.creator.ORCIDhttps://orcid.org/0000-0002-2323-3523pt_BR
dc.creator.ORCIDhttps://orcid.org/0000-0002-3319-5831
dc.date.accessioned2023-04-03T13:19:58Z
dc.date.available2023-04-03T13:19:58Z
dc.date.issued2022
dc.description.abstractObjective: This study aims to evaluate different parameters for determining the inflammatory activity in patients with Chikungunya. Patients and methods: An observational, cross-sectional, descriptive, and analytical study was con ducted with 56 patients from May 2018 to June 2020. Seven independent variables were evaluated [pain in 28 joints, oedema in 28 joints, erythrocyte sedimentation rate, global health assessment, Disease Ac tivity Score 28 (DAS28), pain in 64 joints and oedema in 64 joints] and analysed with a regression mod el to determine their influence on patient satisfaction (dependent variable). Results: All studied variables had a significant influence on patient satisfaction, especially the DAS28. However, the agreement between patient satisfaction and the DAS28 was poor (kappa = 0.2). Thus, new cut-off points were established for the DAS28. Compared to the traditional cut-off points used in rheumatoid arthritis, the new cut-off points increased the accuracy of the DAS28 from 37.5% to 51.8%. Conclusions: This study contributes to the literature by presenting the DAS28 as a potentially useful instrument in patients with Chikungunya and using cut-off points adjusted for this population. The results can serve as a reference for future studies with larger sample sizes, which would allow more definitive conclusions.pt_BR
dc.identifier.citationSÁ, Angela Beatriz de; GOMES, Anna Carolina Padilha Castro. Disease activity Score 28 in patients with Chikungunya vírus infection. Infectious diseases & tropical medicine. [S. l.], v. 8, e 794, p-1-5, jan. 2022. Disponível em: https://bdm.ufpa.br:8443/jspui/handle/prefix/5493. Acesso em:pt_BR
dc.identifier.urihttps://bdm.ufpa.br/handle/prefix/5493
dc.rightsAcesso Abertopt_BR
dc.source.uriDisponível na internet via correio eletrônico: bibsaude@ufpa.brpt_BR
dc.subjectChikungunya feverpt_BR
dc.subjectArbovirus infectionspt_BR
dc.subjectArthritispt_BR
dc.subjectArthralgiapt_BR
dc.subjectDisease activitypt_BR
dc.subject.cnpqCNPQ::CIENCIAS DA SAUDE::MEDICINApt_BR
dc.titleDisease activity Score 28 in patients with Chikungunya virus infectionpt_BR
dc.typeTrabalho de Curso - Graduação - Artigopt_BR

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